These odds are somewhat extreme for football, given the polar opposite talent level of the teams in the standings. If someone put $100 on the Chiefs, they would win $28.57 in profit. Conversely, a bettor on the Bears would make $245 in profit if they bet $100. The -350 odds mean a bettor would have to bet $350 to win $100. In the above example, the Kansas City Chiefs are a strong favorite against the Chicago Bears. Exactly how much of a favorite they are is where moneyline bets get interesting. It would be giving away free money if sportsbooks allowed near even money bets on Alabama or Manchester City in those circumstances.
For example, when Alabama football plays FCS opponents or when Manchester City plays an amateur team in the FA Cup, they are heavily favored.